Types of Ketamine Therapy
People interested in ketamine therapy have several treatments to treat various conditions, including depression, anxiety, and chronic pain. These forms include:
Ketamine is administered as an intravenous (IV) infusion and delivered directly into the bloodstream. IV ketamine therapy allows for rapid symptom relief for acute treatment or maintenance therapy.
Esketamine nasal spray
Esketamine is FDA has approved for treatment-resistant depression. It is administered as a nasal spray and used with an oral antidepressant.
Some studies have suggested that oral ketamine may effectively treat depression and other mental health conditions. However, the oral form of ketamine has a slower onset of action and may not be as effective as intravenous or nasal administration.
It is essential to discuss the potential risks and benefits of ketamine therapy with a qualified healthcare provider before starting treatment.
Benefits & Drawbacks
Intravenous (IV) ketamine infusions:
- Rapid onset of action: Ketamine can start to work within a few hours of receiving an infusion.
- Effectiveness: studies have shown that IV ketamine infusions can reduce symptoms of depression, anxiety, and PTSD in some people.
- Requires a medical setting: IV ketamine infusions must be administered in a medical setting, such as a hospital or clinic, by a healthcare professional.
- Potential side effects: ketamine can cause a range of short-lasting side effects, including dizziness, confusion, and increased heart rate.
Esketamine nasal spray:
- Can be self-administered: intranasal ketamine can be administered at home without needing a healthcare professional to be present.
- Less invasive than IV administration: intranasal administration does not require a needle or intravenous access.
- Esketamine therapy may limit effectiveness: studies have suggested that intranasal ketamine may not be as effective as IV ketamine in treating depression and other mental health conditions.
- Potential for abuse: because it can be self-administered, there is a potential for abuse of intranasal ketamine.
- Convenience: oral ketamine may be more convenient than other forms of administering ketamine therapy.
- Lower bioavailability: Ketamine administered orally is less likely to reach therapeutic levels in the body due to first-pass metabolism (processing by the liver). Ketamine administered orally can limit its effectiveness as a treatment.
- Potential for abuse: like intranasal ketamine, oral ketamine can be abused due to its psychoactive effects.
In conclusion, ketamine therapy offers the potential for rapid symptom relief and may be effective in treating depression, anxiety, and other mental health conditions. However, it is essential to carefully consider the pros and cons of different forms of ketamine therapy and to discuss the risks and benefits with a qualified healthcare provider before starting treatment. Intravenous ketamine infusions offer the potential for rapid symptom relief but must be administered in a medical setting and can cause short-lasting side effects. Intranasal ketamine can be self-administered, but its effectiveness may be limited, and there is a potential for abuse. Oral ketamine may be convenient but has lower bioavailability and potential for abuse. It is essential to carefully weigh the potential risks and benefits of ketamine therapy before starting treatment.