Information for clinicians

All information for clinicians in one place.

We are one of the very few ketamine clinics that utilize the expertise and experience of in-house mental health professionals, from the patient screening process all the way through to post-treatment support. Combining the guidance of mental health professionals with our medical expertise allows us to best tailor the clinical treatment plan to each patient.

Studies by topic

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Role of ketamine for analgesia in adults and children (2016)- PMC – NCBI

פורסם בשנת 2022

Beating pain with psychedelics:Matter over Mind?

פורסם בשנת 2022

Ketamine for suicidal ideation in adults with psychiatric disorders

פורסם בשנת 2019

Ketamine for the acute treatment of severe suicidal ideation:double blind,randomised placebo controlled trial

פורסם בשנת 2022

The rapid anti-suicidal ideation effect of ketamine:systematic review

פורסם בשנת 2020

Ketamine for major depressive disorder in during an inpatient

פורסם בשנת 2024

The research timeline

Ketamine synthesis 1950-1960
Ketamine in animals 1960-1980
Ketamine use for anesthesia 1970-1990
Psychiatric use of ketamine 1990-2020
Ketamine for depression
Ketamine for depression
Ketamine for depression
Ketamine for depression
Ketamine for depression
Ketamine for depression
Ketamine for suicidal thoughts
Ketamine for suicidal thoughts
Ketamine for pain
Ketamine for pain
1959
1973
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1972
1990
1994
2022
2019
2022
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2024
Sernyl (CI-395) in Clinical Anaesthesia
Ketamine anesthesia for rats - ScienceDirect
Effect of ketamine on canine cardiovascular function (one of the first ketamine testing done on animals)
The cataleptic state induced by ketamine - ScienceDirect
Ketamine sedation for pediatric procedures:part 2, reveiw and implications
Subanesthetic Effects of the Noncompetitive NMDA antagonist, Ketamine, in Humans
Maintenance ketamine treatment for depression: a systematic review of efficacy, safety, and tolerability
Efficacy of ketamine therapy in the treatment of depression
Arketamine, a new rapid-acting antidepressant: A historical review
Ketamine for the treatment of major depression:a systematic reveiw and meta-analysis
Ketamine: Mechanisms and Relevance to Treatment of Depression(
Ketamine for major depressive disorder in during an inpatient
Ketamine-Assisted Psychotherapy Provides Lasting and Effective
Anti-Suicidal Effects of IV Ketamine in A Real-World Setting
Efficacy and safety of ketamine and esketamine for unipolar
Ketamine in the Management of Acute Pain
Ketamine in neuropsychiatric disorders: an update

Facts about ketamine

Dosages

I.V. Dose – .2-1 mg/kg body weight 

I.M. Dose- .2-1.5 mg/kg body weight

Chemistry

Formula- C13H16CINO

Molecular weight – 237.73

Melting point – 262-263C (hydrochloride)

Effects

Total duration-  40-90 minutes (depends on speed of administration and dose)

Onset- 5-10 minutes 
peak- 20-40 minutes
come down- 40-90 minutes 
after effects- 1-3 hours 

Positive effects

Neutral effects

Negative effects

Tips for clinicians

keep the environment dimly lit and quite
have an anti nausea medication available (Zofran)
Speak softly and slowly to patients
Don’t rush anyone out of the clinic, let them feel comfortable sitting as long as they want after treatment